ASCO-GI: Overall Survival With Erbitux Is Significantly Improved In Patients With KRAS Wild-Type Tumors In CRYSTAL
January 25, 2010 – 7:23 pmMerck Serono, a division of Merck KGaA, Darmstadt, Germany, announced that Erbitux® (cetuximab) provided an improvement in overall survival (OS) when added to the standard 1st-line FOLFIRI chemotherapy regimen for metastatic colorectal cancer (mCRC) patients with KRAS wild-type tumors in the CRYSTAL study.1 In addition, the final results from this study included an analysis of the predictive value of BRAF status on Erbitux efficacy – one of the first to be based on a large subgroup (n=59) of a prospective, randomized study in the 1st-line setting…
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